Opteron 8220 SE (F2) 's Advantages
Lower TDP (120W vs 170W)
AMD EPYC 7371 's Advantages
Released 12 years and 3 months late
Higher specification of memory (2666 vs 667)
Newer PCIe version (3 vs 1)
Higher base frequency (3.1GHz vs 2.8GHz)
More modern manufacturing process (14nm vs 90nm)