Opteron 8220 SE (F2) 's Advantages
Lower TDP (120W vs 200W)
AMD EPYC 7443 's Advantages
Released 14 years and 7 months late
Higher specification of memory (3200 vs 667)
Newer PCIe version (4 vs 1)
Higher base frequency (2.85GHz vs 2.8GHz)
More modern manufacturing process (7nm vs 90nm)