Opteron 8220 SE (F3) 's Advantages
Higher base frequency (2.8GHz vs 2.7GHz)
Lower TDP (120W vs 210W)
AMD EPYC 9334 's Advantages
Released 16 years and 3 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
More modern manufacturing process (5nm vs 90nm)