Opteron 8220 's Advantages
Higher base frequency (2.8GHz vs 2.15GHz)
Lower TDP (95W vs 100W)
AMD EPYC Embedded 3451 's Advantages
Released 11 years late
Higher specification of memory (2666 vs 667)
Newer PCIe version (3 vs 1)
More modern manufacturing process (14nm vs 90nm)