Opteron 8222 SE 's Advantages
Lower TDP (120W vs 400W)
AMD EPYC 9565 's Advantages
Released 17 years and 6 months late
Higher specification of memory (6000 vs 667)
Newer PCIe version (5 vs 1)
Higher base frequency (3.15GHz vs 3GHz)
More modern manufacturing process (4nm vs 90nm)