Opteron 8222 's Advantages
Higher base frequency (3GHz vs 2.75GHz)
Lower TDP (95W vs 290W)
AMD EPYC 9454 's Advantages
Released 15 years and 3 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
More modern manufacturing process (5nm vs 90nm)