Xeon 6746E 's Advantages
Released 11 years and 7 months late
Higher specification of memory (5600 vs 1866)
Newer PCIe version (5 vs 2)
Larger L3 cache size (96MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)
Opteron 6378 's Advantages
Higher base frequency (2.4GHz vs 2GHz)
Lower TDP (115W vs 250W)