Xeon E 2246G 's Advantages
Higher base frequency (3.6GHz vs 3.2GHz)
Lower TDP (80W vs 95W)
Intel Xeon E 2388G 's Advantages
Released 2 years and 4 months late
Higher specification of memory (3200 vs 2666)
Newer PCIe version (4 vs 3)
Larger L3 cache size (16MB vs 12MB)