Xeon E 2478 's Advantages
Released 11 years late
Higher specification of memory (4800 vs 3)
Larger L3 cache size (24MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)
Lower TDP (80W vs 95W)
Opteron 4386 's Advantages
Higher base frequency (3.1GHz vs 2.8GHz)