Xeon E 2488 's Advantages
Released 12 years and 8 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (24MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)
Intel Xeon E3 1280 's Advantages
Higher base frequency (3.5GHz vs 3.2GHz)