Xeon E 2488 's Advantages
Released 17 years and 4 months late
Higher specification of memory (4800 vs 2)
Newer PCIe version (5 vs 1)
Higher base frequency (3.2GHz vs 2.4GHz)
More modern manufacturing process (10nm vs 90nm)
Opteron 2216 HE (F2) 's Advantages
Lower TDP (68W vs 95W)