AMD Instinct MI300A vs AMD Radeon Instinct MI50
We compared two Professional market GPUs: 128GB VRAM AMD Instinct MI300A and 8GB VRAM Radeon Instinct MI50 to see which GPU has better performance in key specifications, benchmark tests, power consumption, etc.
Main Differences
AMD Instinct MI300A 's Advantages
More VRAM (128GB vs 8GB)
Larger VRAM bandwidth (5300GB/s vs 322.3GB/s)
12544 additional rendering cores
AMD Radeon Instinct MI50 's Advantages
Released 1 years and 5 months late
Boost Clock has increased by 54% (3230MHz vs 2100MHz)
Lower TDP (150W vs 760W)
Score
Benchmark
FP32 (float)
AMD Instinct MI300A
+363%
122.6 TFLOPS
Radeon Instinct MI50
26.46 TFLOPS
Graphics Card
Dec 2023
Release Date
May 2025
Instinct
Generation
Navi IV
Professional
Type
Professional
PCIe 5.0 x16
Bus Interface
PCIe 5.0 x8
Clock Speeds
1000 MHz
Base Clock
2220 MHz
2100 MHz
Boost Clock
3230 MHz
5200 MHz
Memory Clock
2518 MHz
Memory
128GB
Memory Size
8GB
HBM3
Memory Type
GDDR6
8192bit
Memory Bus
128bit
5300GB/s
Bandwidth
322.3GB/s
Render Config
228
Compute Units
32
-
-
-
14592
Shading Units
2048
880
TMUs
128
0
ROPs
64
-
-
-
-
RT Cores
32
16 KB (per CU)
L1 Cache
16 KB (per CU)
16 MB
L2 Cache
4 MB
-
L3 Cache
32 MB
Theoretical Performance
0 MPixel/s
Pixel Rate
206.7 GPixel/s
1496 GTexel/s
Texture Rate
413.4 GTexel/s
980.6 TFLOPS
FP16 (half)
52.92 TFLOPS
122.6 TFLOPS
FP32 (float)
26.46 TFLOPS
61.3 TFLOPS
FP64 (double)
826.9 GFLOPS
Board Design
760W
TDP
150W
1000 W
Suggested PSU
450 W
No outputs
Outputs
1x HDMI 2.1b
3x DisplayPort 2.1a
None
Power Connectors
1x 8-pin
Graphics Processor
MI300
GPU Name
Navi 44
-
GPU Variant
Navi 44 XT
CDNA 3.0
Architecture
RDNA 4.0
TSMC
Foundry
TSMC
5 nm
Process Size
4 nm
146 billion
Transistors
Unknown
1017 mm²
Die Size
153 mm²
Graphics Features
N/A
DirectX
12 Ultimate (12_2)
N/A
OpenGL
4.6
3.0
OpenCL
2.2
N/A
Vulkan
1.3
-
-
-
N/A
Shader Model
6.8
