AMD Radeon R9 M290X 's Advantages
More VRAM (4GB vs 2GB)
Larger VRAM bandwidth (153.6GB/s vs 72.00GB/s)
512 additional rendering cores
AMD Radeon RX 6300M 's Advantages
Released 8 years late
Boost Clock has increased by 167% (2400MHz vs 900MHz)
Lower TDP (35W vs 100W)