AMD Radeon RX 580 's Advantages
Larger VRAM bandwidth (256.0GB/s vs 224.0GB/s)
512 additional rendering cores
AMD Radeon RX 6600 's Advantages
Released 4 years and 6 months late
Boost Clock has increased by 86% (2491MHz vs 1340MHz)
Lower TDP (132W vs 185W)