Qualcomm Snapdragon 821 Advantages
Better graphics card performance FLOPS (0.3343 TFLOPS vs 0.2432 TFLOPS )
Larger memory bandwidth (29.8GB/s vs 14.9GB/s)
Higher Frequency (2342MHz vs 2000MHz)
Qualcomm Snapdragon 665 Advantages
More modern manufacturing process (11nm vs 14nm)
Lower TDP (5W vs 11W)
Released 2 years and 8 months late