AMD EPYC 7451 's Advantages
Lower TDP (180W vs 400W)
AMD EPYC 9745 's Advantages
Released 7 years and 4 months late
Higher specification of memory (6000 vs 2666)
Newer PCIe version (5 vs 3)
Higher base frequency (2.4GHz vs 2.3GHz)
Larger L3 cache size (256MB vs 64MB)
More modern manufacturing process (3nm vs 14nm)