AMD EPYC 7453 's Advantages
Higher base frequency (2.75GHz vs 1.8GHz)
Larger L3 cache size (64MB vs 60MB)
More modern manufacturing process (7nm vs 10nm)
Intel Xeon Gold 6421N 's Advantages
Released 1 years and 10 months late
Higher specification of memory (4400 vs 3200)
Newer PCIe version (5 vs 4)
Lower TDP (185W vs 225W)