AMD EPYC 7501 's Advantages
Released 10 years and 4 months late
Higher specification of memory (2666 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (14nm vs 90nm)
Opteron 2220 's Advantages
Higher base frequency (2.8GHz vs 2GHz)
Lower TDP (95W vs 170W)