AMD EPYC 7543 's Advantages
Released 8 years and 10 months late
Higher specification of memory (3200 vs 3)
Higher base frequency (2.8GHz vs 2.1GHz)
Larger L3 cache size (256MB vs 20MB)
More modern manufacturing process (7nm vs 32nm)
Intel Xeon E5 2450 's Advantages
Lower TDP (95W vs 225W)