AMD EPYC 7643 's Advantages
Released 11 years late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 2)
Higher base frequency (2.3GHz vs 1.9GHz)
Larger L3 cache size (256MB vs 12MB)
More modern manufacturing process (7nm vs 45nm)
Opteron 6168 's Advantages
Lower TDP (115W vs 225W)