AMD EPYC 7643P 's Advantages
Released 10 months late
Lower TDP (225W vs 290W)
AMD EPYC 9454P 's Advantages
Higher specification of memory (4800 vs 3200)
Newer PCIe version (5 vs 4)
Higher base frequency (2.75GHz vs 2.3GHz)
More modern manufacturing process (5nm vs 7nm)