AMD EPYC 9645 's Advantages
Released 10 months late
Higher specification of memory (6000 vs 4800)
Larger L3 cache size (256MB vs 18MB)
More modern manufacturing process (3nm vs 10nm)
Xeon E 2486 's Advantages
Higher base frequency (3.5GHz vs 2.3GHz)
Lower TDP (95W vs 320W)