Intel Xeon E5 1650 v3 's Advantages
Higher base frequency (3.5GHz vs 2.1GHz)
Lower TDP (140W vs 250W)
Intel Xeon Platinum 9221 's Advantages
Released 4 years and 7 months late
Higher specification of memory (DDR4-2933 vs DDR4-2133)
Larger L3 cache size (71.5MB vs 15MB)
More modern manufacturing process (14nm vs 22nm)