Intel Xeon E5 2420 's Advantages
Lower TDP (95W vs 350W)
Intel Xeon w9 3495X 's Advantages
Released 10 years and 9 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Larger L3 cache size (105MB vs 15MB)
More modern manufacturing process (10nm vs 32nm)