Intel Xeon E5 2643 v3 's Advantages
Higher base frequency (3.4GHz vs 3.2GHz)
Larger L3 cache size (20MB vs 16MB)
Intel Xeon E 2388G 's Advantages
Released 7 years late
Higher specification of memory (DDR4-3200 vs DDR4-2133)
Newer PCIe version (4 vs 3)
More modern manufacturing process (14nm vs 22nm)
Lower TDP (95W vs 135W)