Intel Xeon E5 2643 's Advantages
Higher base frequency (3.3GHz vs 2.1GHz)
Lower TDP (130W vs 350W)
Intel Xeon Max 9468 's Advantages
Released 10 years and 10 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (105MB vs 10MB)
More modern manufacturing process (10nm vs 32nm)