Intel Xeon E5 4650 's Advantages
Higher base frequency (2.7GHz vs 2.3GHz)
Lower TDP (130W vs 150W)
Intel Xeon E7 8880 v3 's Advantages
Released 3 years and 1 months late
Higher specification of memory (1866 vs 3)
Larger L3 cache size (45MB vs 20MB)
More modern manufacturing process (22nm vs 32nm)