Intel Xeon Platinum 8380 's Advantages
Released 6 years and 7 months late
Higher specification of memory (DDR4-3200 vs DDR3)
Newer PCIe version (4 vs 3)
Larger L3 cache size (60MB vs 25MB)
More modern manufacturing process (10nm vs 22nm)
Intel Xeon E5 2649 v3 's Advantages
Lower TDP (105W vs 270W)