Intel Xeon Platinum 9221 's Advantages
Released 12 years and 2 months late
Higher specification of memory (2933 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (14nm vs 90nm)
Opteron 2220 's Advantages
Higher base frequency (2.8GHz vs 2.1GHz)
Lower TDP (95W vs 250W)