Intel Xeon Platinum 9221 's Advantages
Released 7 years and 5 months late
Higher specification of memory (DDR4-2933 vs DDR3)
Newer PCIe version (3 vs 2)
Larger L3 cache size (71.5MB vs 8MB)
Opteron 6276 's Advantages
Higher base frequency (2.3GHz vs 2.1GHz)
Lower TDP (115W vs 250W)