Opteron 1389 's Advantages
Higher base frequency (2.9GHz vs 2.3GHz)
Lower TDP (115W vs 225W)
AMD EPYC 7643 's Advantages
Released 11 years and 9 months late
Higher specification of memory (3200 vs 1333)
Newer PCIe version (4 vs 2)
Larger L3 cache size (256MB vs 6MB)
More modern manufacturing process (7nm vs 45nm)