Opteron 2216 HE (F3) 's Advantages
Lower TDP (68W vs 320W)
AMD EPYC 9374F 's Advantages
Released 16 years and 3 months late
Higher specification of memory (4800 vs 2)
Newer PCIe version (5 vs 1)
Higher base frequency (3.85GHz vs 2.4GHz)
More modern manufacturing process (5nm vs 90nm)