Opteron 2216 HE (F3) 's Advantages
Higher base frequency (2.4GHz vs 2.2GHz)
Lower TDP (68W vs 185W)
Intel Xeon Gold 6338N 's Advantages
Released 14 years and 8 months late
Higher specification of memory (2667 vs 2)
Newer PCIe version (4 vs 1)
More modern manufacturing process (10nm vs 90nm)