Opteron 2218 HE 's Advantages
Higher base frequency (2.6GHz vs 2GHz)
Lower TDP (68W vs 170W)
AMD EPYC 7401 's Advantages
Released 10 years and 4 months late
Higher specification of memory (2666 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (14nm vs 90nm)