Opteron 2220 SE (F3) 's Advantages
Lower TDP (119W vs 155W)
AMD EPYC 7302 's Advantages
Released 13 years late
Higher specification of memory (3200 vs 2)
Newer PCIe version (4 vs 1)
Higher base frequency (3GHz vs 2.8GHz)
More modern manufacturing process (7nm vs 90nm)