Opteron 4340 's Advantages
Higher base frequency (3.5GHz vs 3.1GHz)
Lower TDP (95W vs 270W)
Intel Xeon w5 3435X 's Advantages
Released 10 years and 2 months late
Higher specification of memory (4800 vs 3)
Larger L3 cache size (45MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)