Opteron 4386 's Advantages
Higher base frequency (3.1GHz vs 2.55GHz)
Lower TDP (95W vs 160W)
AMD EPYC 8224P 's Advantages
Released 10 years and 9 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Larger L3 cache size (64MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)