Opteron 4386 's Advantages
Higher base frequency (3.1GHz vs 2.75GHz)
Lower TDP (95W vs 290W)
AMD EPYC 9454 's Advantages
Released 9 years and 11 months late
Higher specification of memory (4800 vs 3)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)