Opteron 6168 's Advantages
Lower TDP (115W vs 120W)
AMD EPYC 7272 's Advantages
Released 9 years and 5 months late
Higher specification of memory (DDR4-3200 vs DDR3)
Newer PCIe version (4 vs 2)
Higher base frequency (2.6GHz vs 1.9GHz)
Larger L3 cache size (64MB vs 12MB)
More modern manufacturing process (7nm vs 45nm)