Opteron 6168 's Advantages
Lower TDP (115W vs 225W)
AMD EPYC 7643P 's Advantages
Released 13 years and 6 months late
Higher specification of memory (DDR4-3200 vs DDR3)
Newer PCIe version (4 vs 2)
Higher base frequency (2.3GHz vs 1.9GHz)
Larger L3 cache size (256MB vs 12MB)
More modern manufacturing process (7nm vs 45nm)