Opteron 6180 SE 's Advantages
Higher base frequency (2.5GHz vs 2.1GHz)
AMD EPYC 7251 's Advantages
Released 6 years and 4 months late
Higher specification of memory (2400 vs 1333)
Newer PCIe version (3 vs 2)
Larger L3 cache size (32MB vs 12MB)
More modern manufacturing process (14nm vs 45nm)
Lower TDP (120W vs 140W)