Opteron 6180 SE 's Advantages
Lower TDP (140W vs 200W)
AMD EPYC 9254 's Advantages
Released 11 years and 9 months late
Higher specification of memory (DDR5-4800 vs DDR3-1333)
Newer PCIe version (5 vs 2)
Higher base frequency (2.9GHz vs 2.5GHz)
Larger L3 cache size (128MB vs 12MB)
More modern manufacturing process (5nm vs 45nm)