Opteron 6180 SE 's Advantages
Lower TDP (140W vs 210W)
AMD EPYC 9335 's Advantages
Released 13 years and 8 months late
Higher specification of memory (6000 vs 1333)
Newer PCIe version (5 vs 2)
Higher base frequency (3GHz vs 2.5GHz)
Larger L3 cache size (128MB vs 12MB)
More modern manufacturing process (4nm vs 45nm)