Opteron 6278 's Advantages
Lower TDP (115W vs 200W)
AMD EPYC 9224 's Advantages
Released 10 years and 6 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 2)
Higher base frequency (2.5GHz vs 2.4GHz)
Larger L3 cache size (64MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)