Opteron 6278 's Advantages
Higher base frequency (2.4GHz vs 2GHz)
Lower TDP (115W vs 135W)
Intel Xeon E5 2698B v3 's Advantages
Released 2 years and 8 months late
Higher specification of memory (2133 vs 3)
Newer PCIe version (3 vs 2)
Larger L3 cache size (40MB vs 8MB)
More modern manufacturing process (22nm vs 32nm)