Opteron 6282 SE 's Advantages
Lower TDP (140W vs 225W)
AMD EPYC 7453 's Advantages
Released 9 years and 4 months late
Higher specification of memory (DDR4-3200 vs DDR3)
Newer PCIe version (4 vs 2)
Higher base frequency (2.75GHz vs 2.6GHz)
Larger L3 cache size (64MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)