Opteron 6366 HE 's Advantages
Lower TDP (85W vs 250W)
Intel Xeon Platinum 8380H 's Advantages
Released 8 years and 5 months late
Higher specification of memory (DDR4-3200 vs DDR3)
Newer PCIe version (3 vs 2)
Higher base frequency (2.9GHz vs 1.8GHz)
Larger L3 cache size (38.5MB vs 8MB)