Opteron 6376 's Advantages
Higher base frequency (2.3GHz vs 2.1GHz)
Lower TDP (115W vs 135W)
Intel Xeon E5 4669 v3 's Advantages
Released 2 years and 7 months late
Higher specification of memory (2133 vs 1866)
Newer PCIe version (3 vs 2)
Larger L3 cache size (45MB vs 8MB)
More modern manufacturing process (22nm vs 32nm)