Opteron 6376 's Advantages
Higher base frequency (2.3GHz vs 2.2GHz)
Lower TDP (115W vs 300W)
Intel Xeon Platinum 8461V 's Advantages
Released 10 years and 2 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (97.5MB vs 8MB)