Opteron 6378 's Advantages
Lower TDP (115W vs 200W)
AMD EPYC 8434P 's Advantages
Released 10 years and 10 months late
Higher specification of memory (4800 vs 1866)
Newer PCIe version (5 vs 2)
Higher base frequency (2.5GHz vs 2.4GHz)
Larger L3 cache size (128MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)